D-myo-Inositol 1,3,4,5,6-pentakisphosphate pentapotassium saltReduces the IP4 binding activity of Bruton's tyrosine kinase (Btk)

D-myo-Inositol 1,3,4,5,6-pentakisphosphate pentapotassium salt (CAS 20298-95-7 free acid)

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Synonym: Ins(1,3,4,5,6)P5 . 5K
Application: Reduces the IP4 binding activity of Bruton's tyrosine kinase (Btk)
CAS Number: 20298-95-7 free acid
Purity: ≥98%
Molecular Weight: 770.5
Molecular Formula: C6H12O21P55K
* Refer to Certificate of Analysis for lot specific data (including water content).
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D-myo-Inositol 1,3,4,5,6-pentakisphosphate pentapotassium salt reduces the IP4 binding activity of Bruton's tyrosine kinase (Btk).


References

Synthesis of myo-inositol 1,3,4,5,6-pentakisphosphate from inositol phosphates generated by receptor activation: L.R. Stephens, et al.; Biochem. J. 253, 721 (1988) Inositol 1,3,4,5,6-pentakisphosphate and inositol hexakisphosphate are inhibitors of the soluble inositol 1,3,4,5-tetrakisphosphate 3-phosphatase and the inositol 1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase from pig brai: A. Höer & E. Oberdisse; Biochem. J. 278, 219 (1991) Mutation of the pleckstrin homology domain of Bruton's tyrosine kinase in immunodeficiency impaired inositol 1,3,4,5-tetrakisphosphate binding capacity: M. Fukuda, et al.; J. Biol. Chem. 271, 30303 (1996)

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water.
Storage :
Store at -20° C
Refractive Index :
n20D 1.63 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
SMILES :
[C@H]1([C@@H]([C@H]([C@@H]([C@@H]([C@@H]1O[P](O[H])(=O)[O-])O[P]([O-])(=O)O[H])O[P](O[H])([O-])=O)O[P]([O-])(O[H])=O)O[P](=O)([O-])O[H])O[H].[K+].[K+].[K+].[K+].[K+]

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D-myo-Inositol 1,3,4,5,6-pentakisphosphate pentapotassium salt  Product Citations

See how others have used D-myo-Inositol 1,3,4,5,6-pentakisphosphate pentapotassium salt. Click on the entry to view the PubMed entry .

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PMID: # 24649396  Abe, TK. et al. 2014. FEBS Open Bio. 4: 162-7.

Citations 1 to 1 of 1 total
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