D-Fructose 1,6-bisphosphate trisodium salt octahydrate CAS: 81028-91-3
MF: C6H11O12P2•3Na•8H2O
MW: 550.18
A common metabolic sugar that is an allosteric activator of enzymes such as pyruvate kinase.

D-Fructose 1,6-bisphosphate trisodium salt octahydrate (CAS 81028-91-3)

D-Fructose 1,6-bisphosphate trisodium salt octahydrate | CAS 81028-91-3 is rated 5.0 out of 5 by 1.
  • y_2021, m_7, d_31, h_19
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.18
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_221476, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 122ms
  • REVIEWS, PRODUCT
loading
5
1
4
0
3
0
2
0
1
0
Alternate Names: D-Fructose 1,6-diphosphate trisodium salt; FDP-Na3H
Application: D-Fructose 1,6-bisphosphate trisodium salt octahydrate is a common metabolic sugar that is an allosteric activator of enzymes such as pyruvate kinase
CAS Number: 81028-91-3
Purity: ≥98%
Molecular Weight: 550.18
Molecular Formula: C6H11O12P23Na•8H2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
loading

D-Fructose-1,6-bisphosphate, a common metabolic sugar, is the precursor of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in the glycolytic pathway. D-Fructose 1,6-bisphosphate trisodium salt octahydrate is an activator of PKLR and PKM2. D-Fructose 1,6-bisphosphate trisodium salt octahydrate is also a substrate of Aldolase, liver FBPaseand and muscle FBPase. It is an allosteric activator of enzymes such as pyruvate kinase and a substrate used to identify and characterize enzymes such as fructose-1,6-bisphosphate aldolase(s) and fructose-1, 6-bisphosphatase(s). D-Fructose-1,6-bisphosphate is studied as a neuroprotective agent in brain injury.

Physical State :
Solid
Storage :
Desiccate at 4° C
Melting Point :
100-110° C (dec.)
Density :
~1.65 g/cm3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD00149340
EC Number :
253-778-0
SMILES :
C([[email protected]@H]1[[email protected]]([[email protected]@H]([[email protected]](O1)(COP(=O)(O)[O-])O)O)O)OP(=O)([O-])[O-].O.O.O.O.O.O.O.O.[Na+].[Na+].[Na+]

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 109ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Rated 5 out of 5 by from Song Song, X. et al. (PubMed 16501318) presented evidence that suggests D-Fructose 1,6-bisphosphate (FBP) has a neuroprotective effect against -amyloid induced neurotoxicity in hippocampal slice cultures. Additionally, their research suggests that FBP plays a role not only as an alternative energy source, but also a modulator of PLC and MEK/ERK pathways to regulate the cellular response and survival. -SCBT Publication Review
Date published: 2015-03-06
  • y_2021, m_7, d_31, h_19
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.18
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_221476, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 14ms
  • REVIEWS, PRODUCT