D-Arabinono-1,4-lactone (CAS 2782-09-4)
QUICK LINKS
D-Arabinono-1,4-lactone is instrumental in modulating cellular redox environments and bolstering antioxidant systems, serving as an integral precursor in the biosynthesis pathway of ascorbic acid. D-Arabinono-1,4-lactone is metabolized by the enzyme L-gulono-1,4-lactone oxidase, which facilitates the terminal conversion required for ascorbic acid synthesis in specific organisms. Functionally versatile, D-arabinono-1,4-lactone participates directly in redox reactions, acting as either an electron donor or acceptor, for supporting diverse enzymatic activities. Its role extends to enhancing the efficiency of cellular antioxidant defenses by contributing to the recycling of other antioxidants and safeguarding cellular components against oxidative damage. D-arabinono-1,4-lactone exerts a regulatory influence on gene expression and signaling pathways tailored to manage the oxidative stress response.
D-Arabinono-1,4-lactone (CAS 2782-09-4) References
- D-Erythroascorbic acid is an important antioxidant molecule in Saccharomyces cerevisiae. | Huh, WK., et al. 1998. Mol Microbiol. 30: 895-903. PMID: 10094636
- Bacterial production of D-erythroascorbic acid and L-ascorbic acid through functional expression of Saccharomyces cerevisiae D-arabinono-1,4-lactone oxidase in Escherichia coli. | Lee, BH., et al. 1999. Appl Environ Microbiol. 65: 4685-7. PMID: 10508108
- Deficiency of D-erythroascorbic acid attenuates hyphal growth and virulence of Candida albicans. | Huh, WK., et al. 2001. Infect Immun. 69: 3939-46. PMID: 11349062
- Production of L-ascorbic acid by metabolically engineered Saccharomyces cerevisiae and Zygosaccharomyces bailii. | Sauer, M., et al. 2004. Appl Environ Microbiol. 70: 6086-91. PMID: 15466554
- Copper-ligand complex for the decolorization of synthetic dyes. | Verma, P., et al. 2004. Chemosphere. 57: 1207-11. PMID: 15504481
- D-Erythroascorbic acid activates cyanide-resistant respiration in Candida albicans. | Huh, WK., et al. 2008. Biochem Biophys Res Commun. 369: 401-6. PMID: 18282465
- Production, stability, and antioxidative and antimicrobial activities of two L-ascorbate analogues from phycomyces blakesleeanus: D-erythroascorbate and D-erythroascorbate glucoside. | Gutierrez-Larrainzar, M., et al. 2010. J Agric Food Chem. 58: 10631-8. PMID: 20815349
- Galactonolactone oxidoreductase from Trypanosoma cruzi employs a FAD cofactor for the synthesis of vitamin C. | Kudryashova, EV., et al. 2011. Biochim Biophys Acta. 1814: 545-52. PMID: 21397737
- Efficient Production of Hydroxylated Human-Like Collagen Via the Co-Expression of Three Key Genes in Escherichia coli Origami (DE3). | Tang, Y., et al. 2016. Appl Biochem Biotechnol. 178: 1458-70. PMID: 26712247
- A Putative D-Arabinono-1,4-lactone Oxidase, MoAlo1, Is Required for Fungal Growth, Conidiogenesis, and Pathogenicity in Magnaporthe oryzae. | Wu, MH., et al. 2022. J Fungi (Basel). 8: PMID: 35050012
- Metabolomics Reveals 5-Aminolevulinic Acid Improved the Ability of Tea Leaves (Camellia sinensis L.) against Cold Stress. | Yan, F., et al. 2022. Metabolites. 12: PMID: 35629897
- Changes in the Primary Metabolites of 'Fengtang' Plums during Storage Detected by Widely Targeted Metabolomics. | Lin, X., et al. 2022. Foods. 11: PMID: 36140954
- Characterisation of D-arabinono-1,4-lactone oxidase from Candida albicans ATCC 10231. | Huh, WK., et al. 1994. Eur J Biochem. 225: 1073-9. PMID: 7957197
- D-arabinose dehydrogenase and biosynthesis of erythroascorbic acid in Candida albicans. | Kim, ST., et al. 1996. Biochim Biophys Acta. 1297: 1-8. PMID: 8841374
- D-arabinose dehydrogenase and its gene from Saccharomyces cerevisiae. | Kim, ST., et al. 1998. Biochim Biophys Acta. 1429: 29-39. PMID: 9920381
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
D-Arabinono-1,4-lactone, 1 g | sc-481215 | 1 g | $214.00 |