Cytochalasin C is used in actin polymerization studies. Cytochalasins are potent mycotoxins which bind to the barbed end of actin filaments resulting in inhibition of both the association and dissociation of subunits. Used as a tool for cytological research. These fungal toxins are related by their chemical structure characterized by a highly substituted hydrogenated isoindole ring to which is fused a macrocyclic ring. Cytochalasin C has shown to be 10 times less toxic in mice than cytochalasin D (sc-201442), but with essentially the same biological effectiveness against cells in culture.
Other Cytochalasins available: Cytochalasin A (sc-204705); cytochalasin B (sc-3519); Cytochalasin E, Aspergillus clavatus (sc-202561); Cytochalasin H (sc-202119); Cytochalasin J (sc-202120)
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