cyclin E Antibody (HE111) is a mouse monoclonal IgG1 λ, cited in 133 publications, provided at 200 µg/ml
raised against recombinant cyclin E of human origin
Anti-cyclin E Antibody (HE111) is recommended for detection of cyclin E of mouse, rat and human origin by WB, IP, IF and IHC(P)
Anti-cyclin E Antibody (HE111) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to TRITC for IF, IHC(P) and FCM
TransCruz reagent for Gel Supershift and ChIP applications (sc-248 X, 200 µg/0.1 ml)
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of cyclin E (HE111): sc-248.
At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for cyclin E Antibody (HE111). This work is in progress.
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Labware ships FedEx Ground free of charge to the contiguous US
Cyclins were first identified in invertebrates as proteins that oscillate dramatically through the cell cycle. These proteins have been well conserved through evolution and play a critical role in regulation of cell division. Cyclin E, along with the three cyclin D proteins and cyclin C, has been shown to represent a putative G1 cyclin on the basis of its cyclic pattern of mRNA expression, with maximal levels being detected near the G1/S boundary. Cyclin E has been found to be associated with the transcription factor E2F in a temporally regulated manner. The cyclin E/E2F complex is detected primarily during the G1 phase of the cell cycle and decreases as cells enter S phase. E2F is known to be a critical transcription factor for expression of several S phase specific proteins.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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