Cyanopindolol hemifumarate CAS: 106469-57-2
MF: C16H21N3O2•0.5(C4H4O4)
MW: 345.4
A SR-1A/SR-1B antagonist.

Cyanopindolol hemifumarate (CAS 106469-57-2)

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Application: Cyanopindolol hemifumarate is a SR-1A/SR-1B antagonist
CAS Number: 106469-57-2
Purity: 99%
Molecular Weight: 345.4
Molecular Formula: C16H21N3O20.5(C4H4O4)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Cyanopindolol hemifumarate is a SR-1A and SR-1B antagonist. It is also a AR (β-adrenergic) antagonist.


References

Engel et al (1986) Identity of presynaptic 5-hydroxytryptamine (5-HT) autoreceptors in the rat brain cortex with 5-HT1B binding sites. Naunyn-Schmied.Arch.Pharmacol. 332 1. Blue et al (1989) Interaction of dihydroalprenolol and cyanopindolol with atypical b-adrenoceptors in guinea-pig ileum. Br.J.Pharmacol. 96 246P. Giles et al (1996) Characterization of a 5-HT1B receptor on CHO cells: functional responses in the absence of radioligand binding. Br.J.Pharmacol. 117 1119. Hoey et al (1996) Atypical responses of rat ileum to pindolol, cyanopindolol and iodocyanopindolol. Br.J.Pharmacol. 117 712.

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM), and water (2 mg/ml).
Storage :
Store at room temperature
Melting Point :
250-253° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
MDL Number :
MFCD09878229
SMILES :
CC(C)(C)NCC(COC1=CC=CC2=C1C=C(N2)C#N)O.CC(C)(C)NCC(COC1=CC=CC2=C1C=C(N2)C#N)O.C(=CC(=O)O)C(=O)O

Download SDS (MSDS)

Certificate of Analysis

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