CV 1808CAS: 53296-10-9
MF: C16H18N6O4
MW: 358.36
An Adenosine A2-R agonist.

CV 1808 (CAS 53296-10-9)

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Synonym: 2-Phenylaminoadenosine
Application: An Adenosine A2-R agonist
CAS Number: 53296-10-9
Molecular Weight: 358.36
Molecular Formula: C16H18N6O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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CV 1808 is an Adenosine A2-R agonist, potent coronary vasodilator; weak inhibitor of adenosine uptake by rat cerebral cortical synaptosomes.


References

1. Marumoto, R., et al. 1975. Chem. Pharm. Bull. 23: 759-774. PMID: 1182861
2. Abiru, T., et al. 1991. Eur. J. Pharmacol. 196: 69-76. PMID: 1874281
3. Martin, G.E., et al. 1993. Pharmacol. Biochem. Behav. 45: 951-958.PMID: 8105493

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in methanol (hot), absolute ethanol (slightly), 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin (3.6 mg/ml), and DMSO (10 mM). Insoluble in water.
Storage :
Store at 4° C
Melting Point :
244-246° C
Boiling Point :
~766.0° C at 760 mmHg (Predicted)
Density :
~1.8 g/cm3 (Predicted)
Refractive Index :
n20D 1.83 (Predicted)
IC50 :
Plasmodium falciparum: IC50 = 6.31 µM; Luciferin 4-monooxygenase: EC5050 >0.11 mM
pK Values :
pKa: 13.08 (Predicted), pKb: 4.32 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
AU7413200
PubChem CID :
6917803
MDL Number :
MFCD00055119
SMILES :
C1=CC=C(C=C1)NC2=NC3=C(C(=N2)N)N=CN3[C@H]4[C@@H]([C@@H]([C@H](O4)CO)O)O

Download SDS (MSDS)

Certificate of Analysis

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