CUR 61414CAS: 334998-36-6
MF: C31H42N4O5
MW: 550.69
A mediator of hedgehog signaling pathways.

CUR 61414 (CAS 334998-36-6)

CUR 61414 | CAS 334998-36-6 is rated 5.0 out of 5 by 1.
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Synonym: N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide
Application: A mediator of hedgehog signaling pathways
CAS Number: 334998-36-6
Molecular Weight: 550.69
Molecular Formula: C31H42N4O5
Supplemental Information: This product is subject to an additional Dangerous Goods shipping charge.
* Refer to Certificate of Analysis for lot specific data (including water content).
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CUR 61414 is a proline derivative used as a mediator of hedgehog signaling pathways for pharmaceutical and cosmetic uses.


References

Van der Riet, P., et al.: Cancer Res., 54, 25 (1994), Hahn, H., et al.: Cell, 85, 841 (1996), Johnson, R., et al.: Science, 272, 1668 (1996), Ingham, P., et al.: Genes Dev., 15, 3059 (2001),

Physical State :
Solid
Solubility :
Soluble in chloroform, and methanol.
Storage :
Store at -20° C
Melting Point :
35-40° C (lit.)
Boiling Point :
703.51° C at 760 mmHg (Predicted)
Density :
1.25 g/cm3 (Predicted)
Refractive Index :
n20D 1.62 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
9829015
SMILES :
CC(C)(C)CC(=O)N(CC1=CC(=CC=C1)OC)C2CC(N(C2)CC3=CC4=C(C=C3)OCO4)C(=O)N5CCNCC5

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Stanton et al Stanton et al. (PubMed ID 20024066) found that the Smo modulator, CUR 61414, was a sonic hedgehog signaling pathway inhibitor. -SCBT Publication Review
Date published: 2015-03-04
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