CruzFluor 680 succinimidyl ester MW: 957.17
A fluorophore dye used for labeling proteins, antibodies and nucleic acids.

CruzFluor™ 680 succinimidyl ester

CruzFluor 680 succinimidyl ester is rated 3.0 out of 5 by 2.
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Alternate Names: CFL™ 680 succinimidyl ester
Application: CruzFluor™ 680 succinimidyl ester is a fluorophore dye used for labeling proteins, antibodies and nucleic acids
Molecular Weight: 957.17
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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CruzFluor™ 680 succinimidyl ester dyes display good reactivity, stability as well as selectivity with protein amino groups making them a superb alternative to Cy5.5®, DyLight® 680 and Alexa Fluor® 680 labeling dyes. CruzFluor™ 680 succinimidyl ester dyes have an excitation maxima of ~ 680 nm and emission maxima ~700 nm.
The CruzFluor™ family of products are a fluorescent labeling dye series that spans the full visible spectrum, and are useful to conjugate to nucleic acids, proteins and antibodies. The CruzFluor™ dyes are strong reagents for amine modification because they are incorporated with succinimidyl esters, which have a very strong ability to develop amide bonds that are as stable if not identical to the bonds found on a natural peptide.

Physical State :
Solid
Storage :
Desiccate at -20° C
Fluoresence :
λex 676 nm, λem 695 nm
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Rated 1 out of 5 by from fluorescence quenching after labeling This dye quenches itself when labeled sufficiently strongly, and you end up getting no fluorescence. May be its pi-stacking and quenching fluorescence when labeled strongly, or may be the structure of it is more easy to quench fluorescence when dyes get labeled too close to one another on a protein molecule.. It does react really well though, lysine-targeted reaction under slightly basic conditions. Trying to reduce the labeling efficiency is not very useful either because then you get fluorescence but it ends up too little for my purposes.
Date published: 2021-05-30
Rated 5 out of 5 by from CruzFluor 680 succinimidyl ester has a molecular CruzFluor 680 succinimidyl ester has a molecular weight of ~1900. -SCBT QC
Date published: 2015-04-13
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