Creatinine is a break-down product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body. Creatinine levels in blood and urine may be used to calculate the creatinine clearance (CrCl), which reflects the glomerular filtration rate (GFR), an important clinical index of renal function.
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PMID: # 25407701 Yan, Y.|Zeng, MM.|Zheng, ZP.|He, ZY.|Tao, GJ.|Zhang, S.|Gao, YH.|Chen, J.| et al. 2014. J Agric Food Chem. 62: 11628-36.