Molecular structure of Copper(II) D-gluconate, CAS Number: 527-09-3
Copper(II) D-gluconate (CAS 527-09-3)
Alternate Names:
D-Gluconic acid copper(II) salt
CAS Number:
527-09-3
Molecular Weight:
453.84
Molecular Formula:
C12H22CuO14
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Copper(II) D-gluconate is a compound formed from copper and gluconic acid, a naturally occurring sugar acid. This compound is an essential trace mineral present in numerous foods and plays a critical role in various enzymes. It exhibits a broad spectrum of biochemical effects, including the enhancement of the absorption of minerals such as iron and zinc. It′s believed to act as a chelator, capable of binding to metals and other molecules, influencing their behavior.
Copper(II) D-gluconate (CAS 527-09-3) References
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- Copper improves the anti-angiogenic activity of disulfiram through the EGFR/Src/VEGF pathway in gliomas. | Li, Y., et al. 2015. Cancer Lett. 369: 86-96. PMID: 26254539
- Targeting ALDH1A1 by disulfiram/copper complex inhibits non-small cell lung cancer recurrence driven by ALDH-positive cancer stem cells. | Liu, X., et al. 2016. Oncotarget. 7: 58516-58530. PMID: 27542268
- A novel chemoradiation targeting stem and nonstem pancreatic cancer cells by repurposing disulfiram. | Cong, J., et al. 2017. Cancer Lett. 409: 9-19. PMID: 28864067
- Disulfiram combined with copper inhibits metastasis and epithelial-mesenchymal transition in hepatocellular carcinoma through the NF-κB and TGF-β pathways. | Li, Y., et al. 2018. J Cell Mol Med. 22: 439-451. PMID: 29148232
- Suppressing autophagy enhances disulfiram/copper-induced apoptosis in non-small cell lung cancer. | Wu, X., et al. 2018. Eur J Pharmacol. 827: 1-12. PMID: 29547841
- Process of immunogenic cell death caused by disulfiram as the anti-colorectal cancer candidate. | You, SY., et al. 2019. Biochem Biophys Res Commun. 513: 891-897. PMID: 31003768
- Influence of Mineral Supplementation on the Results from Analysis of Flavonol Glycoside Content in Ginkgo biloba Dietary Supplements. | Lee, JK., et al. 2019. Prev Nutr Food Sci. 24: 75-83. PMID: 31008100
- Induction of autophagy-dependent apoptosis in cancer cells through activation of ER stress: an uncovered anti-cancer mechanism by anti-alcoholism drug disulfiram. | Zhang, X., et al. 2019. Am J Cancer Res. 9: 1266-1281. PMID: 31285958
- Disulfiram/Copper Induces Antitumor Activity against Both Nasopharyngeal Cancer Cells and Cancer-Associated Fibroblasts through ROS/MAPK and Ferroptosis Pathways. | Li, Y., et al. 2020. Cancers (Basel). 12: PMID: 31935835
- Targeting cancer stem cells by disulfiram and copper sensitizes radioresistant chondrosarcoma to radiation. | Wang, K., et al. 2021. Cancer Lett. 505: 37-48. PMID: 33582212
- Improving the Therapeutic Efficacy of Sorafenib for Hepatocellular Carcinoma by Repurposing Disulfiram. | Zhang, G., et al. 2022. Front Oncol. 12: 913736. PMID: 35912209
- Properties of spinel-type Ti-Li-M composite oxides (M = Li, Na, Cu, and Ag) predicted by density functional theory. | Tada, K., et al. 2022. Phys Chem Chem Phys. 24: 28055-28068. PMID: 36377526
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Copper(II) D-gluconate, 100 g | sc-257261 | 100 g | $60.00 |