Copper(II) acetate is used in biochemical applications such as DNA extraction. Copper(II) complexes have been evaluated for anticancer, antibacterial and antifungal activities. Cu(II) complexes are known to cleave DNA; however, increased efficiency is seen in the presence of an oxidizer (often H2O2). Copper acetate exists in a dimeric structure in the solid state as well as in non-aqueous solution. Has been shown to bind the ribose hydroxyls of both purine and pyrimidine nucleosides. Popular methods for DNA extraction may be hindered by endogenous levels of polysaccharides, phenolics and other organic molecules; copper(II) acetate treatment has been shown to fix and remove tannins in samples from Pyrus (Pear) yielding high quality DNA.
1. Devereux, M., et al. 2004. J. Inorg. Biochem. 98: 1023-1031. PMID: 15149811
2. Berger, N.A., et al. 1972. Nature New Biol. 239: 237-240. PMID: 4538853
Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.