Conjugated Linoleic Acid (9Z,11E)The predominant isomer of conjugated linoleic acid in animal tissue

Conjugated Linoleic Acid (9Z,11E) (CAS 2540-56-9)

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Synonym: 9(Z),11(E)-Conjugated Linoleic Acid; Rumenic Acid; 9Z,11E-CLA; Bovinic acid
Application: The predominant isomer of conjugated linoleic acid in animal tissue
CAS Number: 2540-56-9
Molecular Weight: 280.45
Molecular Formula: C18H32O2
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Conjugated Linoleic Acid (9Z,11E) is the predominant isomer of conjugated linoleic acid (CLA) in animal tissue; however, smaller amounts of 10E,12Z also occur. Various antioxidant and antitumor activities have been attributed to CLA or its downstream metabolites. Reported health benefits of dietary supplementation with CLA have been attributed variously to competitive inhibition of Δ6-desaturase and/or PPARγ activation.


References

1. Shultz, T D., et al., 1992. Inhibitory effect of conjugated dienoic derivatives of linoleic acid and beta-carotene on the in vitro growth of human cancer cells. Cancer letters. 63(2): 125-33. PMID: 1562989
2. Houseknecht, K L., et al., 1998. Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat. Biochemical and biophysical research communications. 244(3): 678-82. PMID: 9535724

Formulation :
A solution in 90% ethanol
Physical State :
Liquid
Storage :
Store at -20° C
Boiling Point :
~381.6° C at 760 mmHg (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
5280644
SMILES :
CCCCCC/C=C/C=C/CCCCCCCC(=O)O

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