Concanavalin AA compound that induces apoptosis

Concanavalin A (CAS 11028-71-0)

Concanavalin A | CAS 11028-71-0 is rated 5.0 out of 5 by 2.
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Synonym: ConA
Application: A compound that induces apoptosis
CAS Number: 11028-71-0
Purity: ≥98%
* Refer to Certificate of Analysis for lot specific data (including water content).
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Concanavalin A is a plant lectin that is a T cell mitogen. It induces apoptosis in human fibroblasts.


References

1. Nagase, F., Abo, T., Hiramatsu, K., et al. Microbiol. Immunol. 42:567-74 (1998). PMID: 9776398
2. Kulkarni, G.V., Lee, W., Seth, A., McCulloch, C.A., Exp. Cell. Res. 245:170-8 (1998). PMID: 9828113

Appearance :
Lyophilized powder
Physical State :
Solid
Derived From :
Canavalia ensiformis
Solubility :
Soluble in water(slightly hazy), and PBS (5 mg/mL, slightly hazy).
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
GK6890000
Merck Index :
14: 2495
MDL Number :
MFCD00071069
EC Number :
234-258-2

Download SDS (MSDS)

Certificate of Analysis

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Concanavalin A  Product Citations

See how others have used Concanavalin A. Click on the entry to view the PubMed entry .

Citations 1 to 4 of 4 total

PMID: # 28881670  Zhao, S. et al. 2017. Oncotarget. 8: 51578-51590.

PMID: # 24475786  Castaño, P. et al. 2014. Veterinary research. 45: 9.

PMID: # 24914817  Edaye, S. et al. 2014. Molecular and biochemical parasitology. 195: 34-42.

PMID: # 23696886  Wang, FP. et al. 2013. PLoS ONE. 8: e64373.

Citations 1 to 4 of 4 total

i tried dissolving concanavalin A in PBS at a concentration of 2 mg/ml but unfortunately it produced a turbid solution. I am not quite sure whether I can use for IV injection in rats or not? hope you can help me with this issue thanks

Asked by: Hekmat
Thank you for your question. All Santa Cruz Biotechnology, Inc. reagents are manufactured for in-vitro laboratory use only (RUO). They must not be used in medical diagnostics and they are not to be administered to humans or animals. Concanavalin A (CAS 11028-71-0) is soluble in water(slightly hazy), and PBS (5 mg/mL, slightly hazy). If it cannot be dissolved gentle heating and continual stirring the solvent may be necessary. The solution should always be prepared fresh to avoid precipitation of the solute.
Answered by: SCBT Heidelberg Support
Date published: 2019-01-06

What is this product soluble in?

Asked by: hawkeye11
Thank you for your question. The chemical, sc-203007, should be soluble in water and PBS. We do not have an exact value for water but PBS: soluble 4 % (w/v). We always recommend using solutions right away but if necessary after reconstitution, aliquot and freeze (-20°C). Stock solutions should be stable for up to 6 months at -20°C. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing scbt@scbt.com, or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2017-01-11
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Rated 5 out of 5 by from Works well in application Works well in application.
Date published: 2015-10-12
Rated 5 out of 5 by from Hao Hao, YE. et al. (PubMed 26380813) reported that GIT deficiency attenuates Concanavalin A-induced hepatitis in mice. -SCBT Publication Review
Date published: 2015-02-28
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