CNQX disodium salt is a potent and competitive GluR (kainate/quisqualate (non-NMDA) receptor) antagonist. It also shows antagonism of the NMDA receptor at the glycine modulatory site. It is a more water soluble form of CNQX.
1. Honoré, T., et al. 1988. Science. 241: 701-703. PMID: 2899909 2. Long, S.K., et al. 1990. Br. J. Pharmacol. 100: 850-854. PMID: 1976402 3. Watkins, J.C., et al. 1990. Trends Pharmacol. Sci. 11: 25-33. PMID: 2155495 4. King, A.E., et al. 1992. Br. J. Pharmacol. 107: 375-381. PMID: 1358390
Soluble in water (50 mM).
Store at -20° C
659.3° C at 760 mmHg (Predicted)
n20D ~1.79 (Predicted)
Plasmodium falciparum: IC50 = 10 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Rated 5 out of
Al R; et alAl R; et al. (PubMed ID: 26409118) determined CNQX that disodium salt induced similar TrkB expression levels, however it accounted for a moderate decrease of Hsp70 mRNAs in the same brain areas in hampsters. -SCBT Publication Review
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