Anti-CLC-2 Antibody (D-6) is a mouse monoclonal IgG2b κ CLC-2 antibody, cited in 1 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 859-897 near the C-terminus of CLC-2 of human origin
Anti-CLC-2 Antibody (D-6) is recommended for detection of CLC-2 of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-CLC-2 Antibody (D-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of CLC-2 (D-6): sc-377284.
m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CLC-2 Antibody (D-6) for WB applications. These reagents are now offered in bundles with CLC-2 Antibody (D-6) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
CLC-2 Antibody (D-6) is a high quality monoclonal CLC-2 antibody (also designated CLC-2 antibody) suitable for the detection of the CLC-2 protein of mouse, rat and human origin. CLC-2 Antibody (D-6) is available as both the non-conjugated anti-CLC-2 antibody form, as well as multiple conjugated forms of anti-CLC-2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. CLC-1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC-1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC-2 is highly expressed in the epithelia of several organs including lung, which suggests CLC-2 may be a possible therapeutic target for cystic fibrosis. CLC-3 expression is particularly abundant in neuronal tissue, while CLC-4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC-5 lead to Dent′s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC-6 and CLC-7 are broadly expressed in several tissues including testis, kidney, brain and muscle.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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