Citrinin CAS: 518-75-2
MF: C13H14O5
MW: 250.25
An antibiotic which induces mitochondrial permeability pore opening.

Citrinin (CAS 518-75-2)

Citrinin | CAS 518-75-2 is rated 5.0 out of 5 by 1.
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Alternate Names: 4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid
Application: Citrinin is an antibiotic which induces mitochondrial permeability pore opening
CAS Number: 518-75-2
Molecular Weight: 250.25
Molecular Formula: C13H14O5
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Citrinin is an antibiotic which induces mitochondrial permeability pore opening and inhibits respiration by interfering with complex I of the respiratory chain. Mycotoxin acting as nephrotoxin in all species in which has been tested. Also induces apoptosis.

Physical State :
Solid
Solubility :
Soluble in 100% ethanol, methanol, dichlormethane, and DMSO. Insoluble in water.
Storage :
Store at -20° C
Melting Point :
177.49° C (Predicted)
Boiling Point :
440.63° C at 760 mmHg (Predicted)
Density :
1.38 g/cm3 (Predicted)
Refractive Index :
n20D 1.60 (Predicted)
IC50 :
HL-60 : IC50 = >10 µM (human); KB : IC50 = >10 µM (human); HCT-116: IC50 = >10 µM (human); Amaranthus hypochondriacus: IC50 = 55 µM; Echinochloa crus-galli: IC50 = 63 µM
Ki Data :
OAT3: Ki= 15.4 µM (human); SLC22A11: Ki= 366.4 µM (human); OAT1: Ki= 3080 µM (human)
pK Values :
pKa: 1.52 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
DJ2275000
Transport :
UN 3462, Class 6.1, Packing group III
PubChem CID :
Merck Index :
14: 2327
MDL Number :
MFCD00006912
EC Number :
208-257-2
Beilstein Registry :
5282243
SMILES :
C[[email protected]@H]1[[email protected]](OC=C2C1=C(C(=C(C2=O)C(=O)O)O)C)C

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Certificate of Analysis

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Citrinin (CAS 518-75-2)  Product Citations

See how others have used Citrinin (CAS 518-75-2). Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 31410535  Klingelhöfer, I.|Morlock, GE.| et al. 2019. Anal Bioanal Chem. 411: 6655-6665.

PMID: # 28424858  Anal Bioanal Chem. 4037-4045.

Citations 1 to 2 of 2 total
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Rated 5 out of 5 by from Huertas Huertas-P rez, JF. et al. (PubMed 26125614) created a rapid, simple, and effective method for the determination of the antibiotic Citrinin in rice by ultra-high-performance liquid chromatography and fluorescence detection. Detection and quantification limits were estimated to be 1.5 and 5.0 g kg(-1), respectively. -SCBT Publication Review
Date published: 2015-06-04
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