Citreoviridin CAS: 25425-12-1
MF: C23H30O6
MW: 402.48
A mycotoxin and potent inhibitor of mitochondrial ATPase.

Citreoviridin (CAS 25425-12-1)

Citreoviridin | CAS 25425-12-1 is rated 5.0 out of 5 by 1.
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Alternate Names: Citreoviridin A
Application: Citreoviridin is a mycotoxin and potent inhibitor of mitochondrial ATPase
CAS Number: 25425-12-1
Purity: ≥97%
Molecular Weight: 402.48
Molecular Formula: C23H30O6
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Citreoviridin, a mycotoxin, was initially isolated from Penicillium citreoviride. This agent displays the ability to potently inhibit mitochondrial ATPases via uncompetitive inhibition of ATP hydrolysis. Additional research shows that Citreoviridin can inhibit ATP-driven reduction of NAD+ by succinate and ATP driven NAD transhydrogenase in ox hearts.


References

1. Linnett, P.E., et al. 1978. Biochem. J. 170: 503-510. PMID: 148274
2. Satre, M., et al. 1980. J. Bacteriol. 142: 768-776. PMID: 6445896
3. Gause, E.M., et al. 1981. J. Biol. Chem. 256: 557-559. PMID: 6450205
4. Sayood, S.F., et al. 1989. Arch. Biochem. Biophys. 270: 714-721. PMID: 2523213

Appearance :
Powder
Physical State :
Solid
Derived From :
Penicillium
Solubility :
Soluble in ethanol, chloroform, DMSO, and dichloromethane. Insoluble in water.
Storage :
Store at -20° C
Melting Point :
107-111° C
Boiling Point :
585.12° C at 760 mmHg (Predicted)
Density :
1.19 g/cm3 (Predicted)
Refractive Index :
n20D 1.57 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
UQ1235000
PubChem CID :
Beilstein Registry :
5311865
SMILES :
C[[email protected]@H]1[[email protected]]([[email protected]]([[email protected]](O1)(C)/C=C(\\C)/C=C/C=C/C=C/C2=C(C(=CC(=O)O2)OC)C)O)(C)O

Download SDS (MSDS)

Certificate of Analysis

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Citreoviridin (CAS 25425-12-1)  Product Citations

See how others have used Citreoviridin (CAS 25425-12-1). Click on the entry to view the PubMed entry .

Citations 1 to 2 of 2 total

PMID: # 24318808  Bai, Y. et al. 2015. Environ. Toxicol. 30: 530-7.

PMID: # 26503892  Mol Cell Proteomics. 3284-98.

Citations 1 to 2 of 2 total
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Rated 5 out of 5 by from Sayood et al Sayood et al. (PubMed ID 2523213) showed that Citreoviridin was an uncompetitive inhibitor of ATP hydrolysis and a noncompetitive inhibitor of ATP synthesis catalyzed by membrane-bound F1-ATPase in been heart mitochondria. -SCBT Publication Review
Date published: 2015-06-03
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