Citalopram hydrobromideA highly selective and potent ST inhibitor

Citalopram hydrobromide (CAS 59729-32-7)

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Application: A highly selective and potent ST inhibitor
CAS Number: 59729-32-7
Molecular Weight: 405.31
Molecular Formula: C20H21FN2O.HBr
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* Refer to Certificate of Analysis for lot specific data (including water content).
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Citalopram hydrobromide is a salt form of Citalopram (sc-201123). Citalopram is a selective inhibitor of ST (5-hydroxytryptamine/serotonin transporter) and therefore is a potent and selective serotonin reuptake inhibitor. Additional studies in indicate that Citalopram may be a weak, allosteric modulator of serotonin in a cross-species chimeric study. Studies also indicate that Citalopram is useful for studying gene expression patterns in circulating lymphocytes. In zebrafish, Citalopram is noted to reduce the frequency of NMDA-induced locomotor rhythm involved in swimming behavior.


1. Torres, G.E., et al. 2003. Nat. Rev. Neurosci. 4: 13-25. PMID: 12511858
2. Palotás, A., et al. 2004. Neurochem. Res. 29: 1563-1570. PMID: 15260135
3. Neubauer, H.A., et al. 2006. Mol. Pharmacol. 69: 1242-1250. PMID: 16434615
4. Gabriel, J.P., et al. 2009. J. Neurosci. 29: 10387-10395. PMID: 19692613

Physical State :
Solubility :
Soluble in water (4 mg/ml), methanol, DMSO (25 mg/ml), and ethanol (20 mg/ml).
Storage :
Store at room temperature
Melting Point :
183° C (dec.)
Boiling Point :
428.3° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.59
IC50 :
5-HT uptake: IC50 = 1.8 nM; Plasmodium falciparum: IC50 = 794.33 nM; Noradrenalin uptake: IC50 = 8.8 µM; Dopamine uptake : IC50 = 41 µM
Ki Data :
Serotonin uptake: Ki= 5.4 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 2318
MDL Number :
EC Number :
Beilstein Registry :

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Citalopram hydrobromide  Product Citations

See how others have used Citalopram hydrobromide. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 26338061  Krasulova, K. et al. 2016. Xenobiotica. 46: 315-24.

Citations 1 to 1 of 1 total
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