Citalopram hydrobromide is a salt form of Citalopram (sc-201123). Citalopram is a selective inhibitor of ST (5-hydroxytryptamine/serotonin transporter) and therefore is a potent and selective serotonin reuptake inhibitor. Additional studies in indicate that Citalopram may be a weak, allosteric modulator of serotonin in a cross-species chimeric study. Studies also indicate that Citalopram is useful for studying gene expression patterns in circulating lymphocytes. In zebrafish, Citalopram is noted to reduce the frequency of NMDA-induced locomotor rhythm involved in swimming behavior.
1. Torres, G.E., et al. 2003. Nat. Rev. Neurosci. 4: 13-25. PMID: 12511858 2. Palotás, A., et al. 2004. Neurochem. Res. 29: 1563-1570. PMID: 15260135 3. Neubauer, H.A., et al. 2006. Mol. Pharmacol. 69: 1242-1250. PMID: 16434615 4. Gabriel, J.P., et al. 2009. J. Neurosci. 29: 10387-10395. PMID: 19692613
Soluble in water (4 mg/ml), methanol, DMSO (25 mg/ml), and ethanol (20 mg/ml).
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