Chlortetracycline hydrochlorideA specific and potent calcium ionophore antibiotic

Chlortetracycline hydrochloride (CAS 64-72-2)

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Synonym: Aureomycin HCI; Auxeomycin; Isphamycin
Application: A specific and potent calcium ionophore antibiotic
CAS Number: 64-72-2
Purity: ≥80%
Molecular Weight: 515.34
Molecular Formula: C22H23ClN2O8•HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
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Chlortetracycline Hydrochloride is a specific and potent calcium ionophore antibiotic. The compound has been shown to inhibit binding of aminoacyl-tRNA to ribosomes. In endoplasmic reticulum studies Chortetracycline has been used as a fluorescent dye to analyze calcium changes during apotosis, and in other processes. Chlortetracycline has been shown to block platelet secretion and can affect 17β-estradiol (E2) synthesis in H295R cells. Kupffer cell studies have shown that Chlortetracycline can inhibit secretion of TNF α. We offer the Chlortetracycline Hydrochloride form.


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Appearance :
Physical State :
Derived From :
Isolated from Streptomyces aureofaciens.
Solubility :
Soluble in water (~8.6 mg/mL), methanol (~17.4 mg/mL), ethanol (~1.7 mg/mL), 1 M NaOH (50 mg/mL), and DMSO.
Storage :
Store at -20° C
Melting Point :
210-215° C (lit.)(dec.)
Refractive Index :
n20D ~1.74 (Predicted)
Optical Activity :
α20/D -242.5°, c = 0.5 in water
pK Values :
pKa: 3.3, 7.4, 9.3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 2192
MDL Number :
EC Number :
Beilstein Registry :

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Certificate of Analysis

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