Molecular structure of Chloromethyl ethyl ether, CAS Number: 3188-13-4
Chloromethyl ethyl ether (CAS 3188-13-4)
Alternate Names:
Chloromethoxyethane; Ethoxymethyl chloride
Application:
Chloromethyl ethyl ether is used in the synthesis of HIV-1 reverse transcriptase inhibitiors
CAS Number:
3188-13-4
Purity:
≥95%
Molecular Weight:
94.54
Molecular Formula:
C3H7ClO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Chloromethyl Ethyl Ether is in the synthesis of HIV-1 reverse transcriptase inhibitiors derived from TNK-651. It is a volatile liquid that serves as a solvent in diverse industrial and scientific applications. Notably, it functions as a non-polar solvent, a characteristic that is in organic compound synthesis. This quality allows it to dissolve organic compounds while leaving water-soluble impurities untouched. It serves as a chlorine source, enabling the synthesis of chlorinated compounds.
Chloromethyl ethyl ether (CAS 3188-13-4) References
- Synthesis of non-nucleosides: 7- and 1,3-substituents of new pyrrolo[2,3-d]pyrimidin-4-ones on antiviral activity. | Hilmy, KM. 2006. Arch Pharm (Weinheim). 339: 174-81. PMID: 16586425
- Synthesis of novel uracil non-nucleoside derivatives as potential reverse transcriptase inhibitors of HIV-1. | El-Brollosy, NR., et al. 2009. Arch Pharm (Weinheim). 342: 663-70. PMID: 19856332
- Synthesis and Antiviral Evaluation of 1-[(2-Phenoxyethyl)oxymethyl] and 6-(3,5-Dimethoxybenzyl) Analogues of HIV Drugs Emivirine and TNK-651. | El-Brollosy, NR. and Loddo, R. 2016. Drug Res (Stuttg). 66: 181-8. PMID: 26313923
- Oxidation pathways, kinetics and branching ratios of chloromethyl ethyl ether (CMEE) initiated by OH radicals and the fate of its product radical: an insight from a computational study. | Paul, S., et al. 2019. Environ Sci Process Impacts. 21: 1519-1531. PMID: 31274139
- Process research for the synthesis of RWJ-51204, a novel anxiolytic agent | Cohen, J. H., Maryanoff, C. A., Stefanick, S. M., Sorgi, K. L., & Villani, F. J. 1999. Organic Process Research & Development. 3(4): 260-265.
- Polysulfone/graphene quantum dots composite anion exchange membrane for acid recovery by diffusion dialysis | Yadav, V., Raj, S. K., Rathod, N. H., & Kulshrestha, V. 2020. Journal of Membrane Science. 611: 118331.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Chloromethyl ethyl ether, 25 g | sc-227626 | 25 g | $102.00 |