CetabenCAS: 55986-43-1
MF: C23H39NO2
MW: 361.6
A compound that can permeate the cell and act independent of the PPARα.

Cetaben (CAS 55986-43-1)

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Synonym: Hexadecylamino-p-amino Benzoic Acid
Application: A compound that can permeate the cell and act independent of the PPARα
CAS Number: 55986-43-1
Purity: >98%
Molecular Weight: 361.6
Molecular Formula: C23H39NO2
* Refer to Certificate of Analysis for lot specific data (including water content).
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Peroxisome Proliferator, Cetaben is a compound that can permeate the cell and act independent of the peroxisome proliferator-activated receptor α (PPARα). In addition, it has been shown to inhibit the activity of acyl-CoA:cholesterol acyltransferase (ACAT). The compound has hypolipidemic activity and research shows that it can reduce serum triglyceride and cholesterol concentrations in rats. It has the ability to inhibit cholesterol production in human hepatoma Hep-G2 cells, which can cause reversible changes to the Golgi morphology.


References

1. Albright, J.D., et al. 1983. J. Med. Chem. 26: 1378-1393. PMID: 6604816
2. Chandoga, J., et al. 1994. Biochem. Pharmacol. 47: 515-519. PMID: 8117320
3. Chandoga, J., et al. 1994. Int. J. Biochem. 26: 679-696. PMID: 8005353
4. Kovacs, W., et al. 2001. Histochem. Cell Biol. 115: 509-519. PMID: 11455451
5. Kovacs, W.J., et al. 2004. Histochem. Cell Biol. 122: 95-109. PMID: 15322860

Usage :
For preparation of stock solution, dissolve cataben in an organic solvent purged with an inert gas.
Physical State :
Solid
Solubility :
In DMSO and then diluted in aqueous buffer. Soluble in 0.15mg/ml in a 1:1 solution of DMSO:PBS (pH 7.2). Do not store solution more then one day.
Storage :
Store at 4° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
47263
SMILES :
CCCCCCCCCCCCCCCCNC1=CC=C(C=C1)C(=O)O

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Certificate of Analysis

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Cetaben  Product Citations

See how others have used Cetaben. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 22365411  Kim, Y. et al. 2012. Eur J Med Chem. 50: 311-8.

Citations 1 to 1 of 1 total
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