Cephalosporin Antibody (4i325): sc-70839

Cephalosporin Antibody (4i325) is a mouse monoclonal IgG1 antibody that detects Cephalosporin protein in non-species specific samples by western blotting (WB). Anti-Cephalosporin antibody (4i325) is available as a non-conjugated format, specifically designed to target a class of bactericidal β-lactam antibiotics known for their role in fighting bacterial infections. These antibiotics work by inhibiting peptidoglycan layer synthesis in bacterial cell walls, a key component for bacterial survival. The disruption of this layer leads to bacterial cell lysis and helps treat various infections caused by susceptible organisms. Cephalosporins are grouped into generations based on antimicrobial properties, with each new generation showing improved efficacy against Gram-negative bacteria while often having reduced activity against Gram-positive organisms. Fourth-generation cephalosporins demonstrate true broad-spectrum activity, making them valuable in clinical settings. Understanding how cephalosporins work and their structural features helps optimize their use in therapeutic applications, especially given rising antibiotic resistance.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Cephalosporin Antibody (4i325) References:

1. Which cephalosporin for gonorrhoea?  |  Ison, CA., et al. 2004. Sex Transm Infect. 80: 386-8. PMID: 15459407
2. Correlation of extended spectrum beta lactamases production with cephalosporin resistance in gram negative bacilli.  |  Ghatole, M., et al. 2004. Indian J Pathol Microbiol. 47: 82-4. PMID: 15471144
3. Antistaphylococcal activity of ceftobiprole, a new broad-spectrum cephalosporin.  |  Bogdanovich, T., et al. 2005. Antimicrob Agents Chemother. 49: 4210-9. PMID: 16189100
4. Strain improvement studies on production of cephalosporin C from Acremonium chrysogenum ATCC 48272.  |  Ellaiah, P., et al. Hindustan Antibiot Bull. 45-46: 11-5. PMID: 16281823
5. [Clinical experience with the treatment of severe nosocomial infections by inhibitor-protected 3rd generation cephalosporin cefoperazone/sulbactam].  |  Beloborodova, NV., et al. 2005. Antibiot Khimioter. 50: 33-40. PMID: 16392338
6. Ceftobiprole: in-vivo profile of a bactericidal cephalosporin.  |  Chambers, HF. 2006. Clin Microbiol Infect. 12 Suppl 2: 17-22. PMID: 16524424
7. European Surveillance of Antimicrobial Consumption (ESAC): outpatient cephalosporin use in Europe.  |  Coenen, S., et al. 2006. J Antimicrob Chemother. 58: 413-7. PMID: 16735416
8. The association of third-generation cephalosporin use and invasive candidiasis in extremely low birth-weight infants.  |  Cotten, CM., et al. 2006. Pediatrics. 118: 717-22. PMID: 16882828
9. Outcome of cephalosporin treatment of bacteremia due to CTX-M-type extended-spectrum beta-lactamase-producing Escherichia coli.  |  Bin, C., et al. 2006. Diagn Microbiol Infect Dis. 56: 351-7. PMID: 16934430

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Cephalosporin Antibody (4i325) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Cephalosporin Antibody (4i325) Specifications

Alternate Product Name: Cephalosporin

Product Clone Name: 4i325

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Cephalosporin

Epitope Species:

Product Reactivity/Detection: Cephalosporin

Species Reactivity/Detection: NSR

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB

Vialing Information: Each vial contains 100 µg IgG₁ in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Cephalosporin Antibody (4i325): N/A