CDCAn inhibitor of 5-LO, 12-LO, and 15-LO

CDC (CAS 132465-11-3)

CDC | CAS 132465-11-3 is rated 5.0 out of 5 by 1.
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Application: An inhibitor of 5-LO, 12-LO, and 15-LO
CAS Number: 132465-11-3
Purity: ≥98%
Molecular Weight: 321.3
Molecular Formula: C19H15NO4
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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CDC is a metabolite of ciproflaxacin and is a selective 12-LO (12-lipoxygenase) inhibitor. CDC also inhibits 5-LO and 15-LO.


References

1. Cho, H., et al., 1991. Novel caffeic acid derivatives: extremely potent inhibitors of 12-lipoxygenase. Journal of medicinal chemistry. 34(4): 1503-5. PMID: 2016727

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in ethanol (5 mg/ml), and DMSO (5 mg/ml).
Storage :
Store at room temperature
IC50 :
5-lipoxygenase: IC50 = 15 nM; 12-lipoxygenase: IC50 = 500 nM; 15-lipoxygenase: IC50 = 300 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
9905190
MDL Number :
MFCD00210839
SMILES :
C1=CC=C(C=C1)/C=C/COC(=O)/C(=C\\C2=CC(=C(C=C2)O)O)/C#N

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from CDC was reported in many articles as a metabolite CDC was reported in many articles as a metabolite of ciproflaxacin and a selective inhibitor of 12-lipoxygenase. -SCBT Publication Review
Date published: 2015-04-21
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