Anti-CCDC109A Antibody (E-9) is a mouse monoclonal IgG1 κ CCDC109A antibody, cited in 3 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 110-129 within an internal region of CCDC109A of human origin
Anti-CCDC109A Antibody (E-9) is recommended for detection of CCDC109A of mouse, rat and human origin by WB, IP, IF and ELISA
Anti-CCDC109A Antibody (E-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of CCDC109A (E-9): sc-515930.
m-IgG Fc BP-HRP (mouse IgG Fc binding protein-HRP) and m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) are the preferred secondary detection reagents for CCDC109A Antibody (E-9) for WB applications. These reagents are now offered in bundles with CCDC109A Antibody (E-9) (see ordering information below).
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
CCDC109A Antibody (E-9) is a high quality monoclonal CCDC109A antibody (also designated MCU antibody) suitable for the detection of the CCDC109A protein of mouse, rat and human origin. CCDC109A Antibody (E-9) is available as both the non-conjugated anti-CCDC109A antibody form, as well as multiple conjugated forms of anti-CCDC109A antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. CCDC109A (coiled-coil domain containing 109A), also known as MCU (mitochondrial calcium uniporter), is a 351 amino acid mitochondrial multi-pass membrane protein that belongs to the MCU family. Functioning as a calcium transporter, CCDC109A exists as a homooligomer that interacts with CBARA1 (calcium binding atopy-related autoantigen 1). CCDC109A exists as three alternatively spliced isoforms and is encoded by a gene that maps to human chromosome 10, which contains over 800 genes and 135 million nucleotides, making up nearly 4.5% of the human genome. PTEN is an important tumor suppressor gene located on chromosome 10 and, when defective, causes a genetic predisposition to cancer development known as Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. Tetrahydrobiopterin deficiency and a number of syndromes involving defective skull and facial bone fusion are also linked to chromosome 10. As with most trisomies, trisomy 10 is rare and is deleterious.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences