CB-52MF: C26H43NO3
MW: 417.6
A stable analog of THC and AEA with high affinity for central CB1 and peripheral CB2 receptors.

CB-52

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Application: A stable analog of THC and AEA with high affinity for central CB1 and peripheral CB2 receptors
Molecular Weight: 417.6
Molecular Formula: C26H43NO3
* Refer to Certificate of Analysis for lot specific data (including water content).

CB-52 is a stable analog of Δ9-tetrahydrocannabinol (THC) and anandamide (AEA) which exhibits high affinity for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor with Ki values of 210 and 30 nM, respectively. This compound behaves primarily as a CB1 receptor partial agonist and a CB2 receptor neutral antagonist in vitro.


References

1 Brizzi, A., Brizzi, V., Cascio, M.G., et al. Design, synthesis, and binding studies of new potent ligands of cannabinoid receptors. J Med Chem 48 7343-7350 (2005). 2 Cascio, M.G., Bisogno, T., Palazzo, E., et al. In vitro and in vivo pharmacology of synthetic olivetol- or resorcinol-derived cannabinoid receptor ligands. Br J Pharmacol 149 431-440 (2006).

Physical State :
Solid
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
11495398
SMILES :
CCCCCCC1=C(C=C(C=C1)O)OCCCCCCCCCCC(=O)NC2CC2

Download SDS (MSDS)

Certificate of Analysis

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