CAY15073A nonselective PPAR agonist

CAY15073 (CAS 853652-40-1)

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Synonym: 5-[3-[(6-benzoyl-1-propyl-2-naphthalenyl)oxy]propoxy]-1H-indole-1-acetic acid
Application: A nonselective PPAR agonist
CAS Number: 853652-40-1
Molecular Weight: 521.60
Molecular Formula: C33H33NO5
* Refer to Certificate of Analysis for lot specific data (including water content).
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CAY15073 is a peroxisome proliferator-activated receptor agonist. This compound binds to the γ, α, and β subtypes of PPAR with IC50 values of 50, 113, and 223 nM, respectively.

Physical State :
Solid
Solubility :
Soluble in DMSO (~0.3 mg/ml), and DMF (~0.3 mg/ml).
Storage :
Store at -20° C
Boiling Point :
~737.4° C at 760 mmHg (Predicted)
Density :
~1.2 g/cm3 (Predicted)
Refractive Index :
n20D 1.61 (Predicted)
IC50 :
PPARγ: IC50 = 50 nM; PPARα: IC50 = 113 nM; PPARδ: IC50 = 223 nM; PPARα: EC5050 = 2.48 µM (human); PPARγ: EC5050 = 3.87 µM (human)
pK Values :
pKa: 4.22 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
11678044
SMILES :
CCCC1=C(C=CC2=C1C=CC(=C2)C(=O)C3=CC=CC=C3)OCCCOC4=CC5=C(C=C4)C=CN5CC(=O)O

Download SDS (MSDS)

Certificate of Analysis

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