Catharanthine tartrateA precursor for synthesis of vinblastine and vincristine

Catharanthine tartrate (CAS 4168-17-6)

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Application: A precursor for synthesis of vinblastine and vincristine
CAS Number: 4168-17-6
Molecular Weight: 486.5
Molecular Formula: C21H24N2O2•C4H6O6
* Refer to Certificate of Analysis for lot specific data (including water content).
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Catharanthine tartrate is the starting material for the synthesis of the antitumor drugs vinblastine and vincristine. It is less active as an inhibitor of tubulin self-assembly into microtubules than the latter two compounds.


References

1. Pennanen, S., et al. 1990. Photochem. Photobiol. 51: 515-518. PMID: 2367548
2. Prakash, V. and Timasheff, S.N. 1991. Biochemistry. 30: 873-880. PMID: 1988072

Physical State :
Solid
Derived From :
Catharanthus roseus
Solubility :
Soluble in 100% ethanol
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
SMILES :
C1=CC=CC5=C1C2=C(C3(C4N(CC2)CC(C3)CC4CC)C(=O)OC)[N]5[H].C(C(C(=O)O[H])O[H])(C(=O)O[H])O[H]

Download SDS (MSDS)

Certificate of Analysis

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