caspase-7 p10 Antibody (B-3) is a mouse monoclonal IgG1 (kappa light chain) provided at 200 µg/ml
specific for an epitope mapping between amino acids 257-281 near the C-terminus of caspase-7 p10 of human origin
caspase-7 p10 Antibody (B-3) is recommended for detection of p10 subunit and precursor of caspase-7 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
caspase-7 p10 Antibody (B-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
blocking peptide, sc-365034 P
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of caspase-7 p10 (B-3): sc-365034.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Caspases are cysteine proteases which play important roles in the activation of cytokines and in apoptosis. Caspase-7 is also known as CE-LAP3 (for IL-1 converting enzyme-like apoptotic protease 3), MCH3, and CMH-1. Caspase-7 is a member of the CED-3 subfamily of caspases and is a 303 amino acid protein with significant similarity to caspase-3. Caspase-3 and -7 represent executioner/effector caspases that directly cause apoptotic morphological changes by cleaving various death substrates. The human caspase-7 maps to chromosome 10q25.3 and encodes a protein that is cleaved into p20 and p10 active subunits. The heterodimeric Caspase-7 is activated to its catalytically active large subunit in intact cells undergoing apoptosis. Caspase-7 is a cytoplamic protein expressed in fetal and adult tissues including lung, skeletal muscle, liver, kidney, spleen and heart, as well as various cell lines, such as Jurkat cells.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences