Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
caspase-5 p20 Antibody (H-2) is a high quality monoclonal caspase-5 p20 antibody (also designated Caspase 5 antibody or CASP5 antibody) suitable for the detection of the caspase-5 p20 protein of human origin. caspase-5 p20 Antibody (H-2) is available as the non-conjugated anti-caspase-5 p20 antibody. Caspases are cysteine proteases which play important roles in the activation of cytokines and in apoptosis. The ICE subfamily of caspases comprises peptides closely related to caspase-1, which promotes maturation of interleukin 1β (IL-1β) and interleukin-18 (IL-18) by proteolytic cleavage of precursor forms to generate biologically active peptides. Both caspase-4 and caspase-5 are members of the caspase-1 subfamily, and are more closely related to each other than to other homologues. Caspase-5 (also designated ICErel-III, TY, ICH-3 and caspase-12 in mouse), can cleave its own precursor, an activity that requires the cysteine 245 residue. Frameshift mutations in caspase-5 have been identified in MMP tumors of the endometrium, colon, and stomach, indicating the caspase-5 may be a new target gene in the microsatellite mutator pathway for cancer. The human caspase 5 gene maps to chromosome 11q22.3 and encodes a protein whose expression is barely detectable in most tissues except brain, with highest expression levels being found in lung, liver and skeletal muscle.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
What application is the blocking peptide sc-393346 P appropriate for?
Asked by: AbPolly
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here:
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn