caspase-10 p10 Antibody (E-11) is a mouse monoclonal IgM κ, cited in 1 publications, provided at 200 µg/ml
specific for an epitope mapping between amino acids 458-479 at the C-terminus of caspase-10 p10 of human origin
recommended for detection of caspase-10 p10 subunit and precursor of and human origin by WB, IP, IF, IHC(P) and ELISA
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of caspase-10 p10 (E-11): sc-393983.
m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP) is the preferred secondary detection reagent for caspase-10 p10 Antibody (E-11) for WB and IHC(P) applications. This reagent is now offered in a bundle with caspase-10 p10 Antibody (E-11) (see ordering information below). For additional m-IgGκ BP conjugates see our complete list of Mouse IgG Binding Proteins.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
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Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, Ced-3/caspase-1, is comprised of caspase-1, caspase-2, caspase-3, caspase-4, caspase-6, caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9 and caspase-10. Ced-3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks. Caspase-3, caspase-7 and caspase-9, but not caspase-1, cleave the nuclear protein PARP into an apoptotic fragment. Caspase-6, but not caspase-3, cleaves the nuclear lamins which are critical to maintaining the integrity of the nuclear envelope and cellular morphology. caspase-10 activates caspase-3 and caspase-7 in response to apoptotic stimuli.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.