Carboxyatractyloside potassium salt CAS: 35988-42-2 (non-salt)
MF: C31H46O18S2•xK
MW: 770.82
A highly selective inhibitor of adenine nucleotide translocase (ANT).

Carboxyatractyloside potassium salt (CAS 35988-42-2 (non-salt))

Carboxyatractyloside potassium salt | CAS 35988-42-2 (non-salt) is rated 5.0 out of 5 by 1.
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Alternate Names: C-ATR
Application: Carboxyatractyloside potassium salt is a highly selective inhibitor of adenine nucleotide translocase (ANT)
CAS Number: 35988-42-2 (non-salt)
Purity: ≥98%
Molecular Weight: 770.82
Molecular Formula: C31H46O18S2•xK
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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A highly selective inhibitor of cytosolic side-specific mitochondrial ADP/ATP carriers. For example, adenine nucleotide translocase (ANT) causes stabilization of the c conformation of ANT leading to permeability transition pore (PTP) opening, loss of mitochondrial membrane potential, and eventually apoptosis.


References

Notario, B., et al., All-trans-retinoic acid binds to and inhibits adenine nucleotide translocase and induces mitochondrial permeability transition. Mol. Pharmacol. 63, 224-231, (2003)

Physical State :
Solid
Derived From :
Xanthium sibiricum
Solubility :
Soluble in water ( ≥10 mg/ml).
Storage :
Desiccate at -20° C
Ki Data :
adenine nucleotide translocator (ANT): Ki= <10 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Katz et al Katz et al. (PubMed ID 3571339) found that Carboxyatractyloside potassium salt prevented hepatocyte disintegration via adenine nucleotide translocase inhibition. -SCBT Publication Review
Date published: 2015-05-27
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