CarbimazoleA suppressor of thyroid hormone production

Carbimazole (CAS 22232-54-8)

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Application: A suppressor of thyroid hormone production
CAS Number: 22232-54-8
Purity: ≥98%
Molecular Weight: 186.23
Molecular Formula: C7H10N2O2S
* Refer to Certificate of Analysis for lot specific data (including water content).
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Carbimazole is an effective thyroid hormone inhibitor


References

1. Wise, P.H., et al. 1979. Clin. Endocrinol. 10: 655-664. PMID: 582580

Physical State :
Solid
Solubility :
Soluble in water (2 mg/mL at 20° C), ethanol (1:50), chloroform (1:3), acetone (1:17), and methanol.
Storage :
Store at 4° C
Melting Point :
122-125° C
Boiling Point :
240.4° C
Density :
1.32 g/cm3
Refractive Index :
n20D 1.61
IC50 :
LPO: IC50 = 10.40 µM (human)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
NJ2441000
PubChem CID :
31072
Merck Index :
14: 1798
MDL Number :
MFCD00027421
EC Number :
244-854-4
Beilstein Registry :
144339
SMILES :
CCOC(=O)N1C=CN(C1=S)C

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Certificate of Analysis

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