Caged Retinoic AcidA photoactivatable, caged form of Rentionic Acid.

Caged Retinoic Acid (CAS 1040124-47-7)

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Synonym: Retinoic acid (4,5-dimethoxy-2-nitrophenyl)methyl ester
Application: A photoactivatable, caged form of Rentionic Acid.
CAS Number: 1040124-47-7
Purity: ≥95%
Molecular Weight: 495.6
Molecular Formula: C29H37NO6
* Refer to Certificate of Analysis for lot specific data (including water content).
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Caged Retinoic Acid is a photoactivatable form of Retinoic Acid (sc-200898). Retinoic Acid is the oxidized carboxylic acid form of retinol, known in the dietary context as Vitamin A. Retinal (sc-210778) is the aldehyde form of retinol required by the retina of the eye for light absorption and visual processing. Retinoic acid and the other retinoids are involved in a broad range of biological regulations, mediating differentiation, proliferation, and apoptosis. Binding of Retinoic Acid to the nuclear receptors retinoic acid receptor (RAR) and the retinoid X receptor (RXR) initiate signals for transcription and development. The intimate relationship between retinoids and cell cycle regulation has been implicated in suppression of oncogenic proliferation. Also available as a non-caged form, Retinoic Acid (sc-200898).


References

1. Neveu, P., et al. 2008. Angew. Chem. Int. Ed. Engl. 47: 3744-3746. PMID: 18399559

Physical State :
Solid
Solubility :
Soluble in DMSO (5 mg/ml).
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
MDL Number :
MFCD14635379
SMILES :
COc1cc(COC(=O)/C=C(\\C)/C=C/C=C(\\C)/C=C/C2=C(C)CCCC2(C)C)c(cc1OC)[N+](=O)[O-]

Download SDS (MSDS)

Certificate of Analysis

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