Bupivacaine free base is a local anesthetic which binds to the intracellular portion of sodium channels and blocks sodium influx into the nerve cells, which prevents depolarization. Bupivacaine Free Base is an inhibitor of Sodium Channel Protein.
1. Coskuner, I., et al. 2007. Eur J Anaesthesiol. 24: 535-540. PMID: 17241499 2. Lee, S.J., et al. 2008. Anesth. Analg. 107: 824-827. PMID: 18713891 3. Kucukguclu, S., et al. 2008. Eur J Anaesthesiol. 25: 307-313. PMID: 17888192
Soluble in water, ethanol, chloroform (slightly ), and acetone (slightly ).
Store at room temperature
~423.4° C at 760 mmHg (Predicted)
~1.0 g/cm3 (Predicted)
n20D 1.55 (Predicted)
CYP2D6: IC50 = 400 nM (human); Displacement of [3H]-BTX-B: IC50 = 5.37 µM; Na+ CP type Iα, Na+ CP type IIα, Na+ CP type IIIα: IC50 = 5.4 µM (human); HERG: IC50 = 22 µM (human); Expression of ERG Y652A mutant channel : IC50 = 95 µM (human)
pKb: 8.13 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Can you provide sterile pharma grade bupivacaine (free base)?
Asked by: Or Cohen
No, we do not provide pharmaceutical grade chemicals. Our chemicals are for research use only.
Answered by: Technical Support
Date published: 2018-12-17
The more I buy do it becomes cheaper like if I buy 100 grams of free base bupivacaine how much it will cost me
Asked by: Team player
For bulk order pricing please contact our Special Orders Department. Please call us toll-free at (800) 457-3801 option 2, or email email@example.com.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn
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