BTZO 1 CAS: 99420-15-2
MF: C13H8N2OS
MW: 240.28
A binder of the macrophage migration inhibitory factor (MIF).

BTZO 1 (CAS 99420-15-2)

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Alternate Names: NSC679036
Application: BTZO 1 is a binder of the macrophage migration inhibitory factor (MIF)
CAS Number: 99420-15-2
Molecular Weight: 240.28
Molecular Formula: C13H8N2OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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BTZO 1 is a suppressor of cardiomyocyte apoptosis presumably by activation of antioxidant response element (ARE)-mediated gene expression. BTZO-1 binds to the macrophage migration inhibitory factor (MIF) that is required to activate the glutathione S-transferase Ya subunit (GST Ya) gene ARE.


References

1. Kimura, H. et al. 2010. Chem. Biol. 17(12): 1282-1294. PMID: 21168764

Physical State :
Solid
Solubility :
Soluble in DMSO (≥7 mg/ml).
Storage :
Store at 4° C
Melting Point :
170.59° C (Predicted)
Boiling Point :
~454.9° C at 760 mmHg (Predicted)
Density :
~1.4 g/cm3 (Predicted)
Refractive Index :
n20D 1.71 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
MDL Number :
MFCD19690951
SMILES :
C1=CC=C2C(=C1)C(=O)N=C(S2)C3=CC=CC=N3

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Certificate of Analysis

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