BRL 44408 MALEATECAS: 118343-19-4
MF: C13H17N3 C4H4O4
MW: 331.37
A selective α2A-AR antagonist.

BRL 44408 MALEATE (CAS 118343-19-4)

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Application: A selective α2A-AR antagonist
CAS Number: 118343-19-4
Molecular Weight: 331.37
Molecular Formula: C13H17N3 C4H4O4
* Refer to Certificate of Analysis for lot specific data (including water content).
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BRL 44408 maleate is a selective α2A-AR antagonist. Adrenoreceptors, or adrenergic receptors are G protein-coupled proteins involved in a variety of sympathetic activities. In general, α2A-AR has been associated with regulation of neurotransmitter release from sympathetic nerves. BRL 44408 maleate studies show associated increases hippocampal noradrenaline release following systemic administration.

Physical State :
Solid
Solubility :
Soluble in water (15 mg/mL).
Storage :
Store at room temperature
Refractive Index :
n20D 1.66 (Predicted)
Ki Data :
α2A-adrenoceptor: Ki= 1.7 nM; α2B-adrenergic receptors: Ki= 144.5 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
10382026
MDL Number :
MFCD02262218
SMILES :
CC1N(CC2=NCCN2)CC2=CC=CC=C12

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Certificate of Analysis

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