Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
Botulism is a rare but serious paralytic illness caused by a nerve toxin, which is produced by the bacterium Clostridium botulinum. This neuromuscular disorder occurs through an exquisite series of molecular events, ultimately ending with the arrest of acetylcholine release, resulting in flaccid paralysis. BoNT/B (Botulinum neurotoxin type B), also known as Bontoxilysin B or botB, is a highly toxic 1,291 amino acid secreted protein that exists as a disulfide-linked heterodimer of a heavy chain (H) and a light chain (L). Using zinc as a cofactor, BoNT/B functions as an endopeptidase that cleaves various neuronal proteins, such as VAMP-2, thereby preventing neurotransmitter release. BoNT/B binds to neuronal synapses and is internalized and transported to the spinal cord, where it inserts itself between presynaptic and postsynaptic neurons, inhibiting neurotransmitter release and causing paralysis.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
To place an order using RMB or to ship to mainland China, please visit www.scbio.cn