BohemineA synthetic, cell-permeable, cyclin-dependent kinase inhibitor

Bohemine (CAS 189232-42-6)

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Application: A synthetic, cell-permeable, cyclin-dependent kinase inhibitor
CAS Number: 189232-42-6
Purity: ≥97%
Molecular Weight: 340.43
Molecular Formula: C18H24N6O
* Refer to Certificate of Analysis for lot specific data (including water content).
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Bohemine is a synthetic, cell-permeable, cyclin-dependent kinase (CDK) inhibitor (IC50 = 1 µM) that is structurally similar to Olomoucine and Roscovitine . Arrests cell cycle in the G1/S boundary and activates in vitro matured bovine oocytes either alone or in combination with Ionomycin


References

Chmela, Z., et al. 2001. Drug Metab. Dispos. 29, 326. Alberio, R., et al. 2000. Mol. Reprod. Dev. 55, 422. Binarova, P., et al. 1998. Plant J. 16, 697.

Appearance :
Crystalline
Physical State :
Solid
Solubility :
Soluble in chloroform (50 mg/ml), DMSO or MeOH
Storage :
Store at -20° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
2422
SMILES :
CC(C)N1C=NC2=C1N=C(N=C2NCC3=CC=CC=C3)NCCCO

Download SDS (MSDS)

Certificate of Analysis

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