BMY 7378 dihydrochlorideCAS: 21102-95-4
MF: C22H31N3O3•2HCl
MW: 458.42
A SR-1A agonist and a selective α1D-AR antagonist.

BMY 7378 dihydrochloride (CAS 21102-95-4)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 167ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Synonym: N-(2-(4-(o-Methoxyphenyl)-1-piperazinyl)ethyl)-1,1-cyclopentanediacetimide dihydrochloride
Application: A SR-1A agonist and a selective α1D-AR antagonist
CAS Number: 21102-95-4
Molecular Weight: 458.42
Molecular Formula: C22H31N3O32HCl
* Refer to Certificate of Analysis for lot specific data (including water content).
Submit a review for this product and receive 15 CruzCredits

BMY 7378 dihydrochloride is a putative SR-1A (5-HT1A) partial agonist, and high affinity α1D-AR adrenoceptor antagonist.


1. Sharp, T., et al. 1990. Eur. J. Pharmacol. 176: 331-340. PMID: 1970304
2. Piascik, M.D., et al. 1995. J. Pharmacol. Exp. Ther. 275: 1583-1589. PMID: 8531132
3. Yang, H.T. and Endoh, M. 1997. Br. J. Pharmacol. 122: 1541-1550. PMID: 9422797

Physical State :
Solubility :
Soluble in water (5 mg/ml), DMSO (92 mg/ml), and ethanol (20 mg/ml).
Storage :
Store at 4° C
Melting Point :
196.5-198.5° C
Boiling Point :
585.6° C at 760 mmHg (Predicted)
Refractive Index :
n20D 1.61 (Predicted)
Ki Data :
α1B adrenoceptor : Ki= 0.6 µM (hamster); α1D adrenoceptor : Ki= 2.8 µM (rat); α1A adrenoceptor : Ki= 2.8 µM (rat)
pK Values :
pKb: 7.15 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
MDL Number :

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 100ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 24ms
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2019 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.