BMS 753As been reported to be a RARα-selective agonist

BMS 753 (CAS 215307-86-1)

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Synonym: 4-[[(2,3-Dihydro-1,1,3,3-tetramethyl-2-oxo-1H-inden-5-yl)carbonyl]amino]-benzoic acid
Application: As been reported to be a RARα-selective agonist
CAS Number: 215307-86-1
Purity: ≥98%
Molecular Weight: 351.40
Molecular Formula: C21H21NO4
* Refer to Certificate of Analysis for lot specific data (including water content).

BMS 753 has been reported to be a RARα-selective agonist.


References

1. Taneja, R., et al. 1996. Proc .Natl. Acad. Sci. USA. 93: 6197. PMID: 8650243 2. Dilworth, F.J., et al. 1999. Proc. Natl. Acad. Sci. USA .96: 1995.-2000. PMID: 10051583
3. Gehin, M., et al. 1999. Chem. Biol. 6: 519-529. PMID: 10421757

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM), and ethanol (100 mM).
Storage :
Store at 4° C
Melting Point :
267-267.5° C
Boiling Point :
482.18° C at 760 mmHg (Predicted)
Density :
1.24 g/cm3 (Predicted)
Refractive Index :
n20D 1.61 (Predicted)
Ki Data :
RARα: Ki= 2 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
9884820
MDL Number :
MFCD18384955
SMILES :
CC1(C2=C(C=C(C=C2)C(=O)NC3=CC=C(C=C3)C(=O)O)C(C1=O)(C)C)C

Download SDS (MSDS)

Certificate of Analysis

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