Bisacodyl is a hygroscopic diphenol which has been implicated in the inhibition of (Na+K)ATPase, the increase of mucosal PGE2, and the activation of adenyl cyclase in rat intestine studies.
1. Rachmilewitz, D., et al., 1980. Effects of bisacodyl on cAMP and prostaglandin E2 contents, (Na + K) ATPase, adenyl cyclase, and phosphodiesterase activities of rat intestine. Digestive diseases and sciences. 25(8): 602-8. PMID: 6249558 2. Farack, U M., et al., 1984. Mechanism of action of diphenolic laxatives: the role of adenylate cyclase and mucosal permeability. Digestion. 30(3): 191-4. PMID: 6548720
Soluble in alcohol (slightly), ether (slightly), chloroform, and acetone. Insoluble in water.
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