BIBP 3226 trifluoroacetate CAS: 1068148-47-9
MF: C27H31N5O3•xCF3CO2H
MW: 473.57
An NPY1-R & NPFF2 receptor inhibitor.

BIBP 3226 trifluoroacetate (CAS 1068148-47-9)

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Alternate Names: N-[(1R)]-4-[(Aminoiminomethyl)amino-1-[[[(4-hydroxyphenyl)methyl]amino]carbonyl]butyl-α-phenylbenzeneacetamide ditrifluoroacetate
Application: BIBP 3226 trifluoroacetate is an NPY1-R & NPFF2 receptor inhibitor
CAS Number: 1068148-47-9
Molecular Weight: 473.57
Molecular Formula: C27H31N5O3•xCF3CO2H
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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BIBP 3226 trifluoroacetate is a mixed NPY1-R (non-peptide neuropeptide Y Y1 receptor) and NPFF (neuropeptide FF) receptor inhibitor (Ki values are 1.1, 79, 108, > 1000, > 1000 and >1000 for rNPY1-R, hNPFF2, rNPFF, rNPY2-R, rNPY4-R and rNPY5-R respectively). Following i.c.v. administration, BIBP 3226 trifluoroacetate produces an anxiogenic-like effect in rats.


References

1. Kask, A., et al. 1996. Eur. J. Pharmacol. 317: R3-R4. PMID: 8997632
2. Mollereau, C., et al. 2001. Br. J. Pharmacol. 133: 1-4. PMID: 11325787
3. Fang, Q., et al. 2006. Peptides. 27: 2207-2213. PMID: 16762456

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (10 mM).
Storage :
Store at -20° C
Refractive Index :
n20D 1.63 (Predicted)
Optical Activity :
α20/D 21.4°, c = 1 in water
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
CY1480920
PubChem CID :
56972180
MDL Number :
MFCD09971122
SMILES :
C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)N[[email protected]](CCCN=C(N)N)C(=O)NCC3=CC=C(C=C3)O.C(=O)(C(F)(F)F)O

Download SDS (MSDS)

Certificate of Analysis

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