Bezafibrate is a peroxisome proliferator and hypolipidaemic agent that is a derivative of clofibrate. Shown to be effective in preventing mammary tumors induced by radiation together with DES, possibly by reducing prolactin and triglyceride concentrations. Bezafibrate is an activator of PPARα, PPARβ, PPARγ and LPL.
Inano H, Suzuki K, Wakabayashi K. Carcinogenesis. 17:2641-6 (1996). Goll V, Viollon-Abadie C, Nicod L et al. Hum Exp Toxicol. 19:193-202 (2000).
Soluble in DMSO (50 mg/ml), water (partly), methanol, ethanol (~3 mg/ml), and DMF (~30 mg/ml).
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Rated 5 out of
NoeNoe, N. et al. (PubMed 23261681) reported that Bezafibrate improves mitochondrial function in the CNS of a mouse model of mitochondrial encephalopathy. -SCBT Publication Review
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