Betaxolol hydrochloride CAS: 63659-19-8
MF: C18H29NO3•HCl
MW: 343.89
A selective β1-AR adrenoceptor antagonist.

Betaxolol hydrochloride (CAS 63659-19-8)

Betaxolol hydrochloride | CAS 63659-19-8 is rated 5.0 out of 5 by 1.
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Application: Betaxolol hydrochloride is a selective β1-AR adrenoceptor antagonist
CAS Number: 63659-19-8
Molecular Weight: 343.89
Molecular Formula: C18H29NO3•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Betaxolol hydrochloride is a selective β1-AR adrenoceptor antagonist. Adrenoreceptors, or adrenergic receptors are G protein-coupled proteins involved in a variety of sympathetic nervous system activities. β1-AR is primarily associated with cardiac output effects.


References

1. Beresford,R. and Heel, R.C. 1986. Drugs. 31: 6-28. PMID: 2866947
2. Satoh, E., et al. 1993. Br. J. Pharmacol. 108: 484-489. PMID: 8383566
3 Setoguchi, M., et al. 1995. Br. J. Pharmacol. 115: 198-202. PMID: 7647977

Physical State :
Solid
Solubility :
Soluble in water (50 mM).
Storage :
Store at room temperature
Refractive Index :
n20D ~1.53 (Predicted)
IC50 :
Plasmodium falciparum: IC50 = 6.31 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
UA9823000
PubChem CID :
MDL Number :
MFCD00242959
EC Number :
264-384-3
SMILES :
CC(C)NCC(COC1=CC=C(C=C1)CCOCC2CC2)O.Cl

Download SDS (MSDS)

Certificate of Analysis

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Rated 5 out of 5 by from Setoguchi et al Setoguchi et al. (PubMed ID 7647977) found that Betaxolol hydrochloride inhibited Ca2+ channel currents dose-dependently in both mesenteric artery cells and portal vein cells. -SCBT Publication Review
Date published: 2015-02-25
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