beta-RubromycinCAS: 27267-70-5
MF: C27H20O12
MW: 536.45
A quinone antibiotic agent that inhibits reverse transcriptase.

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β-Rubromycin (CAS 27267-70-5)

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Application: A quinone antibiotic agent that inhibits reverse transcriptase

CAS Number: 27267-70-5

Molecular Weight: 536.45

Molecular Formula: C₂₇H₂₀O₁₂

* Refer to Certificate of Analysis for lot specific data (including water content).

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• SDS & Certificate of Analysis

• Description
• Technical Information
• Safety Information
• SDS & Certificate of Analysis

β-Rubromycin is a quinone antibiotic agent. β-Rubromycin is found to inhibit reverse HIV-1 RT (transcrisptase from HIV-1) to a greater degree than it inhibits cellular DNA polymerase α. This compound also inhibits TERT (human telomerase), and is cytostatically active against different tumor cell lines.

References

Goldman ME, Salituro GS, Bowen JA et al. Mol Pharmacol. 38:20-25 (1990).

Physical State :

Solid

Solubility :

Soluble in chloroform.

Storage :

Store at -20° C

Boiling Point :

~874.8° C at 760 mmHg (Predicted)

Density :

~1.7 g/cm³ (Predicted)

Refractive Index :

n²⁰_D 1.72 (Predicted)

IC50 :

TERT: IC₅₀ = 1.32 µM (human)

pK Values :

pK_a: 7.23 (Predicted)

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

PubChem CID :

5464074

MDL Number :

MFCD03095570

SMILES :

COC1=CC(=C(C2=C1C(=O)C3=C(C2=O)OC4(C3)CCC5=C(O4)C(=C6C(=C5)C=C(OC6=O)C(=O)OC)O)O)OC

Download SDS (MSDS)

Region US - English Brazil - Portuguese Canada - English Canada - French China - Chinese Europe - English Europe - French Europe - German Europe - Italian Europe - Spanish Korea - Korean Japan - Japanese Mexico - Spanish

Certificate of Analysis

Catalog Number sc-204636 sc-204636A

Lot Number

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