Date published: 2025-10-19

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Benzaldehydeoxime (CAS 932-90-1)

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CAS Number:
932-90-1
Molecular Weight:
121.14
Molecular Formula:
C7H7NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Benzaldehydeoxime acts as a competitive inhibitor for the protease enzyme. It establishes covalent bonds with amino acids like serine, cysteine, and threonine located within the enzyme′s active site. The attachment of benzaldoxime to serine and cysteine can be tracked in a kinetic test by observing the liberation of p-nitroanilide from its bonded state with these amino acids.


Benzaldehydeoxime (CAS 932-90-1) References

  1. P450-mediated metabolism of 1-[3-(aminomethyl)phenyl]-N-[3-fluoro-2'-(methylsulfonyl)- [1,1'-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole- 5-carboxamide (DPC 423) and its analogues to aldoximes. Characterization of glutathione conjugates of postulated intermediates derived from aldoximes.  |  Mutlib, AE., et al. 2002. Chem Res Toxicol. 15: 63-75. PMID: 11800598
  2. Structural and mechanistic look at the orthoplatination of aryl oximes by dichlorobis(sulfoxide or sulfide)platinum(II) complexes.  |  Ryabov, AD., et al. 2002. Inorg Chem. 41: 4286-94. PMID: 12160419
  3. Computational study on hydroxybenzotriazoles as reagents for ester hydrolysis.  |  Kumar, VP., et al. 2004. J Org Chem. 69: 8634-42. PMID: 15575739
  4. Electroreduction of aromatic oximes: diprotonation, adsorption, imine formation, and substituent effects.  |  Celik, H., et al. 2006. J Phys Chem B. 110: 6785-96. PMID: 16570986
  5. Effect of structure in benzaldehyde oximes on the formation of aldehydes and nitriles under photoinduced electron-transfer conditions.  |  de Lijser, HJ., et al. 2006. J Org Chem. 71: 7785-92. PMID: 16995687
  6. Mechanistic aspects of the formation of aldehydes and nitriles in photosensitized reactions of aldoxime ethers.  |  de Lijser, HJ., et al. 2007. J Org Chem. 72: 4126-34. PMID: 17477578
  7. Design and synthesis of propeller-shaped dispiroisoxazolinopiperidinochromanones.  |  Carpenter, RD., et al. 2008. J Comb Chem. 10: 225-9. PMID: 18232646
  8. Unusual binding selectivity with non-selective homoditopic pillar[5]arene oxime: serendipitous discovery of a unique approach to heterobinuclear metalation in solution.  |  Yuan, X., et al. 2017. Chem Commun (Camb). 53: 2838-2841. PMID: 28217779
  9. Synthesis of Complex Phenols Enabled by a Rationally Designed Hydroxide Surrogate.  |  Fier, PS. and Maloney, KM. 2017. Angew Chem Int Ed Engl. 56: 4478-4482. PMID: 28337844
  10. An efficient preparation of β-ketophosphine oxides from alkynylphosphine oxides with benzaldehyde oxime as a hydroxide source.  |  Chen, LL., et al. 2019. Org Biomol Chem. 17: 3003-3009. PMID: 30815652
  11. An efficient tandem synthesis of chromones from o-bromoaryl ynones and benzaldehyde oxime.  |  Zhang, JW., et al. 2019. Org Biomol Chem. 17: 7461-7467. PMID: 31360970
  12. Synthesis of Phenols from Aryl Ammonium Salts under Mild Conditions.  |  Ni, P., et al. 2022. J Org Chem. 87: 12677-12687. PMID: 36102897

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Benzaldehydeoxime, 25 g

sc-278729
25 g
$204.00