BC 11-38A selective inhibitor of phosphodiesterase 11

BC 11-38 (CAS 686770-80-9)

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Synonym: 6,7-Dihydro-3-phenyl-2-(propylthio)-thieno[3,2-d]pyrimidin-4(3H)-one
Application: A selective inhibitor of phosphodiesterase 11
CAS Number: 686770-80-9
Purity: ≥98%
Molecular Weight: 304.43
Molecular Formula: C15H16N2OS2
* Refer to Certificate of Analysis for lot specific data (including water content).
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BC 11-38 is a selective PDE11A (phosphodiesterase 11) inhibitor with ain IC50 = 0.28 μM. This compound significantly elevates levels of cAMP by preventing the breakdown of this secondary messenger molecule. This prolongs signal transduction and its subsequent effects.

Physical State :
Solid
Solubility :
Soluble in DMSO (100 mM), and ethanol (20 mM).
Storage :
Store at 4° C
Melting Point :
194.23° C (Predicted)
Boiling Point :
~461.4° C at 760 mmHg (Predicted)
Density :
~1.3 g/cm3 (Predicted)
Refractive Index :
n20D 1.69 (Predicted)
IC50 :
PDE11: IC50 = 0.28 µM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
PubChem CID :
2052828
MDL Number :
MFCD04457614
SMILES :
CCCSC1=NC2=C(C(=O)N1C3=CC=CC=C3)SCC2

Download SDS (MSDS)

Certificate of Analysis

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