Batrachotoxin CAS: 23509-16-2
MF: C31H42N2O6
MW: 538.68
A neurotoxic voltage-gated Na+ channel activator.

Batrachotoxin (CAS 23509-16-2)

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Alternate Names: BTX
Application: Batrachotoxin is a neurotoxic voltage-gated Na+ channel activator
CAS Number: 23509-16-2
Purity: ≥90%
Molecular Weight: 538.68
Molecular Formula: C31H42N2O6
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Batrachotoxin is a toxic steroidal alkaloid, which is found in neotropical poison dart frogs from the genus, Phyllobates. It is known that Batrachotoxin specifically activates sodium channel protein (voltage gated Na+ channels) in the peripheral nervous system, which increase membrane permeability. This alters ion selectivity, prevents channel inactivation, and promotes single channel conductance. Studies determined that the binding site of Batrachotoxin is located within the inner cavity of the voltage gated channel. In addition, the residue hNa(v)1.5-N927 is critical for ion permeation when Batrachotoxin is bound.


References

1. Brown, G.B. 1988. Int. Rev. Neurobiol. 29: 77-116. PMID: 2456998
2. Wang, S.Y., et al. 2006. Mol. Pharmacol. 69: 788-795. PMID: 16354762
3. Wang, S.Y., et al. 2007. Channels 1: 179-188. PMID: 18690024

Appearance :
Film
Physical State :
Solid
Solubility :
Soluble in DMSO, ethanol, and methanol.
Storage :
Store at -20° C
Boiling Point :
~744.0° C at 760 mmHg (Predicted)
Density :
~1.3 g/cm3 (Predicted)
Refractive Index :
n20D 1.64 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
RTECS :
CR3990000
Transport :
Not available for sale outside of the United States.
PubChem CID :
Merck Index :
14: 1009
SMILES :
CC1=CNC(=C1C(=O)OC(C)C2=CC[[email protected]@]34C2(C[[email protected]](C56C3=CC[[email protected]]7[[email protected]@]5(CC[[email protected]@](C7)(O6)O)C)O)CN(CCO4)C)C

Download SDS (MSDS)

Certificate of Analysis

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print and comment on PDF documents

Hola buenas tardes me pued s dar el costo y el tiempo de entrega

Asked by: Anonymous
Thank you for your question. Please contact one of our authorized distributors for information about current product availability and shipping lead times.
Answered by: Technical Support
Date published: 2020-07-16

Hello do u ship in india

Asked by: Gajju
Thank you for your question. Please contact one of our authorized distributors to product availability and shipping lead times.
Answered by: Technical Support
Date published: 2020-02-25

hello, do you ship to the netherlands also?

Asked by: isildur 30
Thank you for your question. Unfortunately, we do not ship this product internationally.
Answered by: Santa Cruz TS
Date published: 2018-08-14

I want to ask you for a formal quotation of BTX CAS 23509-16-2 and importation permissions needed for Colombia. Thanks for your attention

Asked by: Mabel
Thank you for your question. Please contact one of our authorized distributors in Colombia for a formal quotation for this chemical, Batrachotoxin (CAS 23509-16-2). A link to search for our distributors is provided below. https://www.scbt.com/scbt/resources/distributors
Answered by: Technical Support
Date published: 2021-03-22
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