BacitracinA peptide antibiotic and inhibitor of peptidoglycan synthesis

Bacitracin (CAS 1405-87-4)

Bacitracin | CAS 1405-87-4 is rated 5.0 out of 5 by 1.
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Application: A peptide antibiotic and inhibitor of peptidoglycan synthesis
CAS Number: 1405-87-4
Molecular Weight: 1422.69
Molecular Formula: C66H103N17O16S
* Refer to Certificate of Analysis for lot specific data (including water content).
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A peptide antibiotic. Inhibitor of peptidoglycan synthesis. Antimicrobial spectrum: Gram-positive bacteria. Mode of Action: Inhibits bacterial cell wall synthesis by inhibiting dephosphorylation of lipid pyrophosphate. Characterization of the bacte


References

1. J.B. Ward Biochem. J. 141, 227, (1974) 2. A. Anastasi et al. Biochem. J. 290, 601, (1993) 3. D.J. Daly et al. Biochem. Soc. Trans. 13, 1161, (1985) 4. E.D. Weinberg, D. Gottlieb and P.D. Shaw, eds. Antibiotics Berlin , 90, (1967)

Appearance :
Powder
Physical State :
Solid
Derived From :
Bacillus licheniformis
Solubility :
Soluble in Water: 50 mg/mL
Storage :
Store at 4° C
Melting Point :
221-225° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
6714010
SMILES :
CC[C@H](C)[C@H]1C(=O)N[C@@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)NCCCC[C@@H](C(=O)N[C@@H](C(=O)N1)CCCN)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)C2CSC(=N2)C(C(C)CC)N)CC(=O)N)CC(=O)O)CC3=CN=CN3)CC4=CC=CC=C4

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Certificate of Analysis

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Bacitracin  Product Citations

See how others have used Bacitracin. Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 25697356  Zhao, G. et al. 2015. The Journal of biological chemistry. 290: 8949-63.

Citations 1 to 1 of 1 total
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Rated 5 out of 5 by from Androwkiki et al Androwkiki et al. (PubMed ID 28570854) found that the protein disulfide isomerase inhibitor, bacitracin, decreased Ang II redox signaling (p-ERK 1/2) in hypertension patients. -SCBT Publication Review
Date published: 2015-05-01
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